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Short-term culture of tumour slices reveals the heterogeneous sensitivity of human head and neck squamous cell carcinoma to targeted therapies

BACKGROUND: Despite recent progress, investigating the impact of targeted therapies on Head and Neck Squamous Cell Carcinoma (HNSCC) remains a challenge. We investigated whether short-term culture of tumour fragments would permit the evaluation of tumour sensitivity to targeted therapies at the indi...

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Detalles Bibliográficos
Autores principales: Donnadieu, Jérôme, Lachaier, Emma, Peria, Marine, Saidak, Zuzana, Dakpe, Stéphanie, Ikoli, Jean-Fortune, Chauffert, Bruno, Page, Cyril, Galmiche, Antoine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4834185/
https://www.ncbi.nlm.nih.gov/pubmed/27085492
http://dx.doi.org/10.1186/s12885-016-2318-x