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Hijacking the Hexosamine Biosynthetic Pathway to Promote EMT-Mediated Neoplastic Phenotypes

The epithelial–mesenchymal transition (EMT) is a highly conserved program necessary for orchestrating distant cell migration during embryonic development. Multiple studies in cancer have demonstrated a critical role for EMT during the initial stages of tumorigenesis and later during tumor invasion....

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Detalles Bibliográficos
Autores principales: Taparra, Kekoa, Tran, Phuoc T., Zachara, Natasha E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4834358/
https://www.ncbi.nlm.nih.gov/pubmed/27148477
http://dx.doi.org/10.3389/fonc.2016.00085