microRNA let-7c is essential for the anisomycin-elicited apoptosis in Jurkat T cells by linking JNK1/2 to AP-1/STAT1/STAT3 signaling

Anisomycin, an antibiotic produced by Streptomyces griseolus, strongly induces apoptosis in various tumor cells in vitro, superior dramatically to adriamycin. The present study aims to elucidate its detailed mechanistic process. The results showed that anisomycin sufficiently promoted the apoptosis...

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Detalles Bibliográficos
Autores principales: Zhou, Zhiwei, Lu, Xijian, Wang, Jin, Xiao, Jia, Liu, Jing, Xing, Feiyue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4834478/
https://www.ncbi.nlm.nih.gov/pubmed/27087117
http://dx.doi.org/10.1038/srep24434

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4834478/
https://www.ncbi.nlm.nih.gov/pubmed/27087117
http://dx.doi.org/10.1038/srep24434

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