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Quantifying the effect of Vpu on the promotion of HIV-1 replication in the humanized mouse model
BACKGROUND: Tetherin is an intrinsic anti-viral factor impairing the release of nascent HIV-1 particles from infected cells. Vpu, an HIV-1 accessory protein, antagonizes the anti-viral action of tetherin. Although previous studies using in vitro cell culture systems have revealed the molecular mecha...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4834825/ https://www.ncbi.nlm.nih.gov/pubmed/27086687 http://dx.doi.org/10.1186/s12977-016-0252-2 |