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Tissue plasminogen activator (tPA) attenuates propofol-induced apoptosis in developing hippocampal neurons

BACKGROUND: We investigated the effect of propofol on the tissue plasminogen activator (tPA) release in developing hippocampal neurons, and explored the effects of exogenous tPA on the propofol-induced neuron apoptosis. METHODS: Primary hippocampal neurons isolated from neonatal Sprague-Dawley rats...

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Detalles Bibliográficos
Autores principales: Liang, Chao, Ding, Ming, Du, Fang, Cang, Jing, Xue, Zhanggang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4835406/
https://www.ncbi.nlm.nih.gov/pubmed/27217990
http://dx.doi.org/10.1186/s40064-016-2091-y