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How SUMOylation Fine-Tunes the Fanconi Anemia DNA Repair Pathway
Fanconi anemia (FA) is a rare human genetic disorder characterized by developmental defects, bone marrow failure and cancer predisposition, primarily due to a deficiency in the repair of DNA interstrand crosslinks (ICLs). ICL repair through the FA DNA repair pathway is a complicated multi-step proce...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Frontiers Media S.A.
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4835495/ https://www.ncbi.nlm.nih.gov/pubmed/27148358 http://dx.doi.org/10.3389/fgene.2016.00061 |