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Genetic risk variants in the CDKN2A/B, RTEL1 and EGFR genes are associated with somatic biomarkers in glioma

During the last years, genome wide association studies have discovered common germline genetic variants associated with specific glioma subtypes. We aimed to study the association between these germline risk variants and tumor phenotypes, including copy number aberrations and protein expression. A t...

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Detalles Bibliográficos
Autores principales: Ghasimi, Soma, Wibom, Carl, Dahlin, Anna M., Brännström, Thomas, Golovleva, Irina, Andersson, Ulrika, Melin, Beatrice
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4835517/
https://www.ncbi.nlm.nih.gov/pubmed/26839018
http://dx.doi.org/10.1007/s11060-016-2066-4