Amplicon-based semiconductor sequencing of human exomes: performance evaluation and optimization strategies

The Ion Proton platform allows to perform whole exome sequencing (WES) at low cost, providing rapid turnaround time and great flexibility. Products for WES on Ion Proton system include the AmpliSeq Exome kit and the recently introduced HiQ sequencing chemistry. Here, we used gold standard variants f...

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Detalles Bibliográficos
Autores principales: Damiati, E., Borsani, G., Giacopuzzi, Edoardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2016
Materias:
Original Investigation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4835520/
https://www.ncbi.nlm.nih.gov/pubmed/27003585
http://dx.doi.org/10.1007/s00439-016-1656-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4835520/
https://www.ncbi.nlm.nih.gov/pubmed/27003585
http://dx.doi.org/10.1007/s00439-016-1656-8

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