Allele-specific transcription factor binding to common and rare variants associated with disease and gene expression

Genome-wide association studies (GWAS) have identified a large number of disease-associated SNPs, but in few cases the functional variant and the gene it controls have been identified. To systematically identify candidate regulatory variants, we sequenced ENCODE cell lines and used public ChIP-seq d...

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Detalles Bibliográficos
Autores principales: Cavalli, Marco, Pan, Gang, Nord, Helena, Wallerman, Ola, Wallén Arzt, Emelie, Berggren, Olof, Elvers, Ingegerd, Eloranta, Maija-Leena, Rönnblom, Lars, Lindblad Toh, Kerstin, Wadelius, Claes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2016
Materias:
Original Investigation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4835527/
https://www.ncbi.nlm.nih.gov/pubmed/26993500
http://dx.doi.org/10.1007/s00439-016-1654-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4835527/
https://www.ncbi.nlm.nih.gov/pubmed/26993500
http://dx.doi.org/10.1007/s00439-016-1654-x

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