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Signalling couples hair follicle stem cell quiescence with reduced histone H3 K4/K9/K27me3 for proper tissue homeostasis

Mechanisms of plasticity to acquire different cell fates are critical for adult stem cell (SC) potential, yet are poorly understood. Reduced global histone methylation is an epigenetic state known to mediate plasticity in cultured embryonic SCs and T-cell progenitors. Here we find histone H3 K4/K9/K...

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Detalles Bibliográficos
Autores principales: Lee, Jayhun, Kang, Sangjo, Lilja, Karin C., Colletier, Keegan J., Scheitz, Cornelia Johanna Franziska, Zhang, Ying V., Tumbar, Tudorita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4835553/
https://www.ncbi.nlm.nih.gov/pubmed/27080563
http://dx.doi.org/10.1038/ncomms11278