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Prostacyclin-producing human mesenchymal cells target H19 lncRNA to augment endogenous progenitor function in hindlimb ischaemia

Promoting the paracrine effects of human mesenchymal stem cell (hMSC) therapy may contribute to improvements in patient outcomes. Here we develop an innovative strategy to enhance the paracrine effects of hMSCs. In a mouse hindlimb ischaemia model, we examine the effects of hMSCs in which a novel tr...

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Detalles Bibliográficos
Autores principales: Deng, Yuxiao, Yang, Zhongwei, Terry, Toya, Pan, Su, Woodside, Darren G., Wang, Jingxiong, Ruan, Kehe, Willerson, James T., Dixon, Richard A. F., Liu, Qi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4835554/
https://www.ncbi.nlm.nih.gov/pubmed/27080438
http://dx.doi.org/10.1038/ncomms11276