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Erythroleukemia cells acquire an alternative mitophagy capability

Leukemia cells are superior to hematopoietic cells with a normal differentiation potential in buffering cellular stresses, but the underlying mechanisms for this leukemic advantage are not fully understood. Using CRISPR/Cas9 deletion of the canonical autophagy-essential gene Atg7, we found that eryt...

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Detalles Bibliográficos
Autores principales: Wang, Jian, Fang, Yixuan, Yan, Lili, Yuan, Na, Zhang, Suping, Xu, Li, Nie, Meilan, Zhang, Xiaoying, Wang, Jianrong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4835698/
https://www.ncbi.nlm.nih.gov/pubmed/27091640
http://dx.doi.org/10.1038/srep24641