Cellular uptake of exogenous calcineurin B is dependent on TLR4/MD2/CD14 complexes, and CnB is an endogenous ligand of TLR4

Our previous research showed that recombinant calcineurin B (rhCnB) stimulates cytokine secretion by immune cells, probably through TLR4. Exogenous CnB can be incorporated into many different tumour cells in vitro, but the mode of uptake and receptors required remain unknown. Here, we report that ex...

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Detalles Bibliográficos
Autores principales: Yang, Jinju, Qin, Nannan, Zhang, Hongwei, Yang, Rui, Xiang, Benqiong, Wei, Qun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4835703/
https://www.ncbi.nlm.nih.gov/pubmed/27090571
http://dx.doi.org/10.1038/srep24346

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4835703/
https://www.ncbi.nlm.nih.gov/pubmed/27090571
http://dx.doi.org/10.1038/srep24346

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