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Do piperacillin/tazobactam and other antibiotics with inhibitory activity against Clostridium difficile reduce the risk for acquisition of C. difficile colonization?

BACKGROUND: Systemic antibiotics vary widely in in vitro activity against Clostridium difficile. Some agents with activity against C. difficile (e.g., piperacillin/tazobactam) inhibit establishment of colonization in mice. We tested the hypothesis that piperacillin/tazobactam and other agents with a...

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Detalles Bibliográficos
Autores principales: Kundrapu, Sirisha, Sunkesula, Venkata C. K., Jury, Lucy A., Cadnum, Jennifer L., Nerandzic, Michelle M., Musuuza, Jackson S., Sethi, Ajay K., Donskey, Curtis J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4835867/
https://www.ncbi.nlm.nih.gov/pubmed/27091232
http://dx.doi.org/10.1186/s12879-016-1514-2