Multiallelic copy number variation in the complement component 4A (C4A) gene is associated with late-stage age-related macular degeneration (AMD)

BACKGROUND: Age-related macular degeneration (AMD) is the leading cause of vision loss in Western societies with a strong genetic component. Candidate gene studies as well as genome-wide association studies strongly implicated genetic variations in complement genes to be involved in disease risk. So...

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Detalles Bibliográficos
Autores principales: Grassmann, Felix, Cantsilieris, Stuart, Schulz-Kuhnt, Anja-Sabrina, White, Stefan J., Richardson, Andrea J, Hewitt, Alex W, Vote, Brendan J., Schmied, Denise, Guymer, Robyn H, Weber, Bernhard H.F., Baird, Paul N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4835888/
https://www.ncbi.nlm.nih.gov/pubmed/27090374
http://dx.doi.org/10.1186/s12974-016-0548-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4835888/
https://www.ncbi.nlm.nih.gov/pubmed/27090374
http://dx.doi.org/10.1186/s12974-016-0548-0

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