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Lung tumor exosomes induce a pro-inflammatory phenotype in mesenchymal stem cells via NFκB-TLR signaling pathway

BACKGROUND: In tumor microenvironment, a continuous cross-talk between cancer cells and other cellular components is required to sustain tumor progression. Accumulating evidence suggests that exosomes, a novel way of cell communication, play an important role in such cross-talk. Exosomes could facil...

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Detalles Bibliográficos
Autores principales: Li, Xiaoxia, Wang, Shihua, Zhu, Rongjia, Li, Hongling, Han, Qin, Zhao, Robert Chunhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4836087/
https://www.ncbi.nlm.nih.gov/pubmed/27090786
http://dx.doi.org/10.1186/s13045-016-0269-y