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Hypoxia-induced modulation of PTEN activity and EMT phenotypes in lung cancers

BACKGROUND: Persistent hypoxia stimulation, one of the most critical microenvironmental factors, accelerates the acquisition of epithelial–mesenchymal transition (EMT) phenotypes in lung cancer cells. Loss of phosphatase and tensin homologue deleted from chromosome 10 (PTEN) expression might acceler...

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Detalles Bibliográficos
Autores principales: Kohnoh, Takashi, Hashimoto, Naozumi, Ando, Akira, Sakamoto, Koji, Miyazaki, Shinichi, Aoyama, Daisuke, Kusunose, Masaaki, Kimura, Motohiro, Omote, Norihito, Imaizumi, Kazuyoshi, Kawabe, Tsutomu, Hasegawa, Yoshinori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4836157/
https://www.ncbi.nlm.nih.gov/pubmed/27095949
http://dx.doi.org/10.1186/s12935-016-0308-3