Cargando…

Hypoxia-induced modulation of PTEN activity and EMT phenotypes in lung cancers

BACKGROUND: Persistent hypoxia stimulation, one of the most critical microenvironmental factors, accelerates the acquisition of epithelial–mesenchymal transition (EMT) phenotypes in lung cancer cells. Loss of phosphatase and tensin homologue deleted from chromosome 10 (PTEN) expression might acceler...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kohnoh, Takashi, Hashimoto, Naozumi, Ando, Akira, Sakamoto, Koji, Miyazaki, Shinichi, Aoyama, Daisuke, Kusunose, Masaaki, Kimura, Motohiro, Omote, Norihito, Imaizumi, Kazuyoshi, Kawabe, Tsutomu, Hasegawa, Yoshinori
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Primary Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4836157/ https://www.ncbi.nlm.nih.gov/pubmed/27095949 http://dx.doi.org/10.1186/s12935-016-0308-3

Ejemplares similares

Direct regulation of transforming growth factor β‐induced epithelial–mesenchymal transition by the protein phosphatase activity of unphosphorylated PTEN in lung cancer cells
por: Kusunose, Masaaki, et al.
Publicado: (2015)

Involvement of TGFβ-Induced Phosphorylation of the PTEN C-Terminus on TGFβ-Induced Acquisition of Malignant Phenotypes in Lung Cancer Cells
por: Aoyama, Daisuke, et al.
Publicado: (2013)

Repressive role of stabilized hypoxia inducible factor 1α expression on transforming growth factor β‐induced extracellular matrix production in lung cancer cells
por: Ando, Akira, et al.
Publicado: (2019)

Impact of mild to moderate COPD on feasibility and prognosis in non-small cell lung cancer patients who received chemotherapy
por: Omote, Norihito, et al.
Publicado: (2017)

CD40/CD40 LIGAND INTERACTIONS IN IMMUNE RESPONSES AND PULMONARY IMMUNITY
por: KAWABE, TSUTOMU, et al.
Publicado: (2011)

High-flow nasal cannula therapy for acute respiratory failure in patients with interstitial pneumonia: a retrospective observational study
por: Omote, Norihito, et al.
Publicado: (2020)

Successful Treatment with High-dose Steroids for Acute Exacerbation of Idiopathic Pulmonary Fibrosis Triggered by COVID-19
por: Omote, Norihito, et al.
Publicado: (2021)

COVID-19-Triggered Acute Exacerbation of IPF, an Underdiagnosed Clinical Entity With Two-Peaked Respiratory Failure: A Case Report and Literature Review
por: Goto, Yosuke, et al.
Publicado: (2022)

Long noncoding RNA TINCR is a novel regulator of human bronchial epithelial cell differentiation state
por: Omote, Norihito, et al.
Publicado: (2021)

Protective effects of intratracheally administered quercetin on lipopolysaccharide-induced acute lung injury
por: Takashima, Koji, et al.
Publicado: (2014)

Clinical impact of prevalence and severity of COPD on the decision-making process for therapeutic management of lung cancer patients
por: Hashimoto, Naozumi, et al.
Publicado: (2014)

Pirfenidone as salvage treatment for refractory bleomycin-induced lung injury: a case report of seminoma
por: Sakamoto, Koji, et al.
Publicado: (2017)

A case of pulmonary actinomycosis diagnosed by transbronchial lung biopsy
por: Nakamura, Saya, et al.
Publicado: (2017)

TGF-β isoforms induce EMT independent migration of ovarian cancer cells
por: Gao, Jingfang, et al.
Publicado: (2014)

Identification and clinical validation of EMT-associated prognostic features based on hepatocellular carcinoma
por: Xu, Dafeng, et al.
Publicado: (2021)

MicroRNA-492 expression promotes the progression of hepatic cancer by targeting PTEN
por: Jiang, Jianxin, et al.
Publicado: (2014)

PARG deficiency is neither synthetic lethal with BRCA1 nor PTEN deficiency
por: Noll, Aurélia, et al.
Publicado: (2016)

Cisplatin loaded multiwalled carbon nanotubes reverse drug resistance in NSCLC by inhibiting EMT
por: Qi, Yuxin, et al.
Publicado: (2021)

Diagnostic contribution of cytological examination to endobronchial ultrasound-guided transbronchial biopsy for lung malignancies
por: Kajikawa, Shigehisa, et al.
Publicado: (2019)

MicroRNA-524 promotes cell proliferation by down-regulating PTEN expression in osteosarcoma
por: Zhuang, Ming, et al.
Publicado: (2018)

MiR-4310 induced by SP1 targets PTEN to promote glioma progression
por: Wu, Zhiyong, et al.
Publicado: (2020)

Inhibitory role of ATF3 in gastric cancer progression through regulating cell EMT and stemness
por: Huang, Chuanqian, et al.
Publicado: (2021)

CTCF-silenced miR-137 contributes to EMT and radioresistance in esophageal squamous cell carcinoma
por: Xu, Shuwen, et al.
Publicado: (2021)

Acute exacerbation of rheumatoid arthritis-associated interstitial lung disease triggered by COVID-19: What is the best practice for treatment?
por: Yonezawa, Toshiyuki, et al.
Publicado: (2023)

Knockdown of PSCA induces EMT and decreases metastatic potentials of the human prostate cancer DU145 cells
por: Kang, Ran, et al.
Publicado: (2016)

M2 macrophages secrete CXCL13 to promote renal cell carcinoma migration, invasion, and EMT
por: Xie, Yingwei, et al.
Publicado: (2021)

MiR-214 regulate gastric cancer cell proliferation, migration and invasion by targeting PTEN
por: Yang, Ting-Song, et al.
Publicado: (2013)

TRIM27 promotes the development of esophagus cancer via regulating PTEN/AKT signaling pathway
por: Ma, Liang, et al.
Publicado: (2019)

YAP manipulates proliferation via PTEN/AKT/mTOR-mediated autophagy in lung adenocarcinomas
por: Xu, Wei, et al.
Publicado: (2021)

Hypoxia and TGF-β1 induced PLOD2 expression improve the migration and invasion of cervical cancer cells by promoting epithelial-to-mesenchymal transition (EMT) and focal adhesion formation
por: Xu, Feifei, et al.
Publicado: (2017)

HOXB8 enhances the proliferation and metastasis of colorectal cancer cells by promoting EMT via STAT3 activation
por: Wang, Tingting, et al.
Publicado: (2019)

As a biomarker for gastric cancer, circPTPN22 regulates the progression of gastric cancer through the EMT pathway
por: Ma, Shuo, et al.
Publicado: (2021)

CMTM3 suppresses chordoma progress through EGFR/STAT3 regulated EMT and TP53 signaling pathway
por: Yuan, Wanqiong, et al.
Publicado: (2021)

LINC01410 leads the migration, invasion and EMT of bladder cancer cells by modulating miR-4319 / Snail1
por: Guo, Wei, et al.
Publicado: (2021)

Activation of synovial fibroblasts in rheumatoid arthritis: lack of expression of the tumour suppressor PTEN at sites of invasive growth and destruction
por: Pap, Thomas, et al.
Publicado: (2000)

Cell migration and proliferation are regulated by miR-26a in colorectal cancer via the PTEN–AKT axis
por: Coronel-Hernández, Jossimar, et al.
Publicado: (2019)

Acute respiratory distress syndrome due to severe pulmonary tuberculosis treated with extracorporeal membrane oxygenation: A case report and review of the literature
por: Omote, Norihito, et al.
Publicado: (2016)

PTBP3 promotes migration of non-small cell lung cancer through regulating E-cadherin in EMT signaling pathway
por: Wu, Qiong, et al.
Publicado: (2020)

CDCA4 suppresses epithelial–mesenchymal transtion (EMT) and metastasis in Non-small cell lung cancer through modulating autophagy
por: Xu, Chenxin, et al.
Publicado: (2021)

Piezo1 promoted hepatocellular carcinoma progression and EMT through activating TGF-β signaling by recruiting Rab5c
por: Li, Yi-ming, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_8clg43fpccot63kfc77mq2nhkf