Calpain 3 deficiency affects SERCA expression and function in the skeletal muscle

Limb-girdle muscular dystrophy type 2A (LGMD2A) is a form of muscular dystrophy caused by mutations in calpain 3 (CAPN3). Several studies have implicated Ca(2+) dysregulation as an underlying event in several muscular dystrophies, including LGMD2A. In this study we used mouse and human myotube cultu...

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Detalles Bibliográficos
Autores principales: Toral-Ojeda, Ivan, Aldanondo, Garazi, Lasa-Elgarresta, Jaione, Lasa-Fernández, Haizpea, Fernández-Torrón, Roberto, López de Munain, Adolfo, Vallejo-Illarramendi, Ainara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cambridge University Press 2016
Materias:
Discovery
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4836212/
https://www.ncbi.nlm.nih.gov/pubmed/27055500
http://dx.doi.org/10.1017/erm.2016.9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4836212/
https://www.ncbi.nlm.nih.gov/pubmed/27055500
http://dx.doi.org/10.1017/erm.2016.9

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