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Novel Role for Protein Inhibitor of Activated STAT 4 (PIAS4) in the Restriction of Herpes Simplex Virus 1 by the Cellular Intrinsic Antiviral Immune Response

Small ubiquitin-like modifier (SUMO) is used by the intrinsic antiviral immune response to restrict viral pathogens, such as herpes simplex virus 1 (HSV-1). Despite characterization of the host factors that rely on SUMOylation to exert their antiviral effects, the enzymes that mediate these SUMOylat...

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Detalles Bibliográficos
Autores principales: Conn, Kristen L., Wasson, Peter, McFarlane, Steven, Tong, Lily, Brown, James R., Grant, Kyle G., Domingues, Patricia, Boutell, Chris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4836348/
https://www.ncbi.nlm.nih.gov/pubmed/26937035
http://dx.doi.org/10.1128/JVI.03055-15