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Clusters of specialized detector cells provide sensitive and high fidelity receptor signaling in the intact endothelium

Agonist-mediated signaling by the endothelium controls virtually all vascular functions. Because of the large diversity of agonists, each with varying concentrations, background noise often obscures individual cellular signals. How the endothelium distinguishes low-level fluctuations from noise and...

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Detalles Bibliográficos
Autores principales: Wilson, Calum, Saunter, Christopher D., Girkin, John M., McCarron, John G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Federation of American Societies for Experimental Biology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4836367/
https://www.ncbi.nlm.nih.gov/pubmed/26873937
http://dx.doi.org/10.1096/fj.201500090