Stimulated Whole Blood Cytokine Release as a Biomarker of Immunosuppression in the Critically Ill: The Need for a Standardized Methodology

OBJECTIVE: Reduced ex vivo lipopolysaccharide (LPS) stimulated whole blood pro-inflammatory cytokine release is a hallmark of immunosuppression in the critically ill and predicts adverse clinical outcomes. No standard technique for performing the assay currently exists. The impact of methodological...

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Detalles Bibliográficos
Autores principales: Segre, Elisabetta, Fullerton, James N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2016
Materias:
Rapid Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4836558/
https://www.ncbi.nlm.nih.gov/pubmed/27089173
http://dx.doi.org/10.1097/SHK.0000000000000557

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4836558/
https://www.ncbi.nlm.nih.gov/pubmed/27089173
http://dx.doi.org/10.1097/SHK.0000000000000557

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