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Profilin modulates sarcomeric organization and mediates cardiomyocyte hypertrophy

AIMS: Heart failure is often preceded by cardiac hypertrophy, which is characterized by increased cell size, altered protein abundance, and actin cytoskeletal reorganization. Profilin is a well-conserved, ubiquitously expressed, multifunctional actin-binding protein, and its role in cardiomyocytes i...

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Detalles Bibliográficos
Autores principales: Kooij, Viola, Viswanathan, Meera C., Lee, Dong I., Rainer, Peter P., Schmidt, William, Kronert, William A., Harding, Sian E., Kass, David A., Bernstein, Sanford I., Van Eyk, Jennifer E., Cammarato, Anthony
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4836629/
https://www.ncbi.nlm.nih.gov/pubmed/26956799
http://dx.doi.org/10.1093/cvr/cvw050