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Prior activation of inositol 1,4,5-trisphosphate receptors suppresses the subsequent induction of long-term potentiation in hippocampal CA1 neurons

We investigated the role of inositol 1,4,5-trisphosphate receptors (IP(3)Rs) activated by preconditioning low-frequency afferent stimulation (LFS) in the subsequent induction of long-term potentiation (LTP) in CA1 neurons in hippocampal slices from mature guinea pigs. Induction of LTP in the field e...

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Detalles Bibliográficos
Autores principales: Fujii, Satoshi, Yamazaki, Yoshihiko, Goto, Jun-Ichi, Fujiwara, Hiroki, Mikoshiba, Katsuhiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4836634/
https://www.ncbi.nlm.nih.gov/pubmed/27084928
http://dx.doi.org/10.1101/lm.041053.115