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Trans and cis factors affecting A-to-I RNA editing efficiency of a noncoding editing target in C. elegans

Adenosine-to-inosine RNA editing by ADARs affects thousands of adenosines in an organism's transcriptome. However, adenosines are not edited at equal levels nor do these editing levels correlate well with ADAR expression levels. Therefore, additional mechanisms are utilized by the cell to dicta...

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Detalles Bibliográficos
Autores principales: Washburn, Michael C., Hundley, Heather A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4836646/
https://www.ncbi.nlm.nih.gov/pubmed/26917557
http://dx.doi.org/10.1261/rna.055079.115