Tetrabromobisphenol A Is an Efficient Stabilizer of the Transthyretin Tetramer

Amyloid formation of the human plasma protein transthyretin (TTR) is associated with several human disorders, including familial amyloidotic polyneuropathy (FAP) and senile systemic amyloidosis. Dissociation of TTR’s native tetrameric assembly is the rate-limiting step in the conversion into amyloid...

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Detalles Bibliográficos
Autores principales: Iakovleva, Irina, Begum, Afshan, Brännström, Kristoffer, Wijsekera, Alexandra, Nilsson, Lina, Zhang, Jin, Andersson, Patrik L., Sauer-Eriksson, A. Elisabeth, Olofsson, Anders
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4836675/
https://www.ncbi.nlm.nih.gov/pubmed/27093678
http://dx.doi.org/10.1371/journal.pone.0153529

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4836675/
https://www.ncbi.nlm.nih.gov/pubmed/27093678
http://dx.doi.org/10.1371/journal.pone.0153529

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