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Clinical Validation of Therapeutic Drug Monitoring of Imipenem in Spent Effluent in Critically Ill Patients Receiving Continuous Renal Replacement Therapy: A Pilot Study

OBJECTIVES: The primary objective of this pilot study was to investigate whether the therapeutic drug monitoring of imipenem could be performed with spent effluent instead of blood sampling collected from critically ill patients under continuous renal replacement therapy. METHODS: A prospective open...

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Detalles Bibliográficos
Autores principales: Wen, Aiping, Li, Zhe, Yu, Junxian, Li, Ren, Cheng, Sheng, Duan, Meili, Bai, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4836878/
https://www.ncbi.nlm.nih.gov/pubmed/27093294
http://dx.doi.org/10.1371/journal.pone.0153927