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Light Controlled Modulation of Gene Expression by Chemical Optoepigenetic Probes

Epigenetic gene regulation is a dynamic process orchestrated by chromatin-modifying enzymes. Many of these master regulators exert their function through covalent modification of DNA and histone proteins. Aberrant epigenetic processes have been implicated in the pathophysiology of multiple human dis...

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Detalles Bibliográficos
Autores principales: Reis, Surya A., Ghosh, Balaram, Hendricks, J. Adam, Szantai-Kis, D. Miklos, Törk, Lisa, Ross, Kenneth N., Lamb, Justin, Read-Button, Willis, Zheng, Baixue, Wang, Hongtao, Salthouse, Christopher, Haggarty, Stephen J., Mazitschek, Ralph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4836974/
https://www.ncbi.nlm.nih.gov/pubmed/26974814
http://dx.doi.org/10.1038/nchembio.2042