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Light Controlled Modulation of Gene Expression by Chemical Optoepigenetic Probes
Epigenetic gene regulation is a dynamic process orchestrated by chromatin-modifying enzymes. Many of these master regulators exert their function through covalent modification of DNA and histone proteins. Aberrant epigenetic processes have been implicated in the pathophysiology of multiple human dis...
Autores principales: | Reis, Surya A., Ghosh, Balaram, Hendricks, J. Adam, Szantai-Kis, D. Miklos, Törk, Lisa, Ross, Kenneth N., Lamb, Justin, Read-Button, Willis, Zheng, Baixue, Wang, Hongtao, Salthouse, Christopher, Haggarty, Stephen J., Mazitschek, Ralph |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4836974/ https://www.ncbi.nlm.nih.gov/pubmed/26974814 http://dx.doi.org/10.1038/nchembio.2042 |
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