Cargando…
Late stages of T cell maturation in the thymus involve NF-κB and tonic type I interferon signaling
Positive selection occurs in the thymic cortex, but critical maturation events occur later in the medulla. We defined the precise stage at which T cells acquire competence to proliferate and emigrate. Transcriptome analysis of late gene changes suggested roles for NF-κB and interferon (IFN) signalin...
| Autores principales: | , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2016
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4837029/ https://www.ncbi.nlm.nih.gov/pubmed/27043411 http://dx.doi.org/10.1038/ni.3419 |