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Steric trapping reveals a cooperativity network in the intramembrane protease GlpG

Membrane proteins are assembled through balanced interactions among protein, lipids and water. Studying their folding while maintaining the native lipid environment is necessary but challenging. Here we present methods for analyzing key elements in membrane protein folding including thermodynamic st...

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Detalles Bibliográficos
Autores principales: Guo, Ruiqiong, Gaffney, Kristen, Yang, Zhongyu, Kim, Miyeon, Sungsuwan, Suttipun, Huang, Xuefei, Hubbell, Wayne L., Hong, Heedeok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4837050/
https://www.ncbi.nlm.nih.gov/pubmed/26999782
http://dx.doi.org/10.1038/nchembio.2048