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Steric trapping reveals a cooperativity network in the intramembrane protease GlpG
Membrane proteins are assembled through balanced interactions among protein, lipids and water. Studying their folding while maintaining the native lipid environment is necessary but challenging. Here we present methods for analyzing key elements in membrane protein folding including thermodynamic st...
Autores principales: | Guo, Ruiqiong, Gaffney, Kristen, Yang, Zhongyu, Kim, Miyeon, Sungsuwan, Suttipun, Huang, Xuefei, Hubbell, Wayne L., Hong, Heedeok |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4837050/ https://www.ncbi.nlm.nih.gov/pubmed/26999782 http://dx.doi.org/10.1038/nchembio.2048 |
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