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N-cadherin functions as a growth suppressor in a model of K-ras-induced PanIN

Cadherin subtype switching from E-cadherin to N-cadherin is associated with the epithelial-to-mesenchymal transition (EMT), a process required for invasion and dissemination of carcinoma cells. We found N-cadherin is expressed in human and mouse pancreatic intraepithelial neoplasia (PanIN), suggesti...

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Detalles Bibliográficos
Autores principales: Su, Yanrong, Li, Jifen, Shi, Chanjuan, Hruban, Ralph H., Radice, Glenn L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4837100/
https://www.ncbi.nlm.nih.gov/pubmed/26477318
http://dx.doi.org/10.1038/onc.2015.382