Cargando…
N-cadherin functions as a growth suppressor in a model of K-ras-induced PanIN
Cadherin subtype switching from E-cadherin to N-cadherin is associated with the epithelial-to-mesenchymal transition (EMT), a process required for invasion and dissemination of carcinoma cells. We found N-cadherin is expressed in human and mouse pancreatic intraepithelial neoplasia (PanIN), suggesti...
Autores principales: | Su, Yanrong, Li, Jifen, Shi, Chanjuan, Hruban, Ralph H., Radice, Glenn L. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4837100/ https://www.ncbi.nlm.nih.gov/pubmed/26477318 http://dx.doi.org/10.1038/onc.2015.382 |
Ejemplares similares
-
Precursor Lesions for Sporadic Pancreatic Cancer: PanIN, IPMN, and MCN
por: Distler, M., et al.
Publicado: (2014) -
Expression of SNAIL in accompanying PanIN is a key prognostic indicator in pancreatic ductal adenocarcinomas
por: Fujiwara, Sho, et al.
Publicado: (2019) -
Acinar-to-Ductal Metaplasia (ADM): On the Road to Pancreatic Intraepithelial Neoplasia (PanIN) and Pancreatic Cancer
por: Marstrand-Daucé, Louis, et al.
Publicado: (2023) -
N-cadherin acts upstream of VE-cadherin in controlling vascular morphogenesis
por: Luo, Yang, et al.
Publicado: (2005) -
Smad4 Loss Synergizes with TGFα Overexpression in Promoting Pancreatic Metaplasia, PanIN Development, and Fibrosis
por: Garcia-Carracedo, Dario, et al.
Publicado: (2015)