A novel protein isoform of the RON tyrosine kinase receptor transforms human pancreatic duct epithelial cells

The MST1R gene is overexpressed in pancreatic cancer producing elevated levels of the RON tyrosine kinase receptor protein. While mutations in MST1R are rare, alternative splice variants have been previously reported in epithelial cancers. We report the discovery of a novel RON isoform discovered in...

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Detalles Bibliográficos
Autores principales: Chakedis, Jeffery, French, Randall, Babicky, Michele, Jaquish, Dawn, Howard, Haleigh, Mose, Evangeline, Lam, Raymond, Holman, Patrick, Miyamoto, Jaclyn, Walterscheid, Zakk, Lowy, Andrew M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4837108/
https://www.ncbi.nlm.nih.gov/pubmed/26477314
http://dx.doi.org/10.1038/onc.2015.384

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4837108/
https://www.ncbi.nlm.nih.gov/pubmed/26477314
http://dx.doi.org/10.1038/onc.2015.384

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