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TGF-β signaling links E-cadherin loss to suppression of nucleotide excision repair

E-cadherin is a cell adhesion molecule best known for its function in suppressing tumor progression and metastasis. Here we show that E-cadherin promotes nucleotide excision repair through positively regulating the expression of xeroderma pigmentosum complementation group C (XPC) and DNA damage-bind...

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Detalles Bibliográficos
Autores principales: Qiang, Lei, Shah, Palak, Barcellos-Hoff, Mary Helen, He, Yu-Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4837109/
https://www.ncbi.nlm.nih.gov/pubmed/26477308
http://dx.doi.org/10.1038/onc.2015.390