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The effects of arginine glutamate, a promising excipient for protein formulation, on cell viability: Comparisons with NaCl

The effects of an equimolar mixture of l-arginine and l-glutamate (Arg·Glu) on cell viability and cellular stress using in vitro cell culture systems are examined with reference to NaCl, in the context of monoclonal antibody formulation. Cells relevant to subcutaneous administration were selected: t...

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Detalles Bibliográficos
Autores principales: Kheddo, Priscilla, Golovanov, Alexander P., Mellody, Kieran T., Uddin, Shahid, van der Walle, Christopher F., Dearman, Rebecca J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Pergamon Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4837223/
https://www.ncbi.nlm.nih.gov/pubmed/26873863
http://dx.doi.org/10.1016/j.tiv.2016.02.002