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Brain-derived neurotrophic factor promotes nerve regeneration by activating the JAK/STAT pathway in Schwann cells

BACKGROUND: Radical prostatectomy (RP) carries the risk of erectile dysfunction (ED) due to cavernous nerve (CN) injury. Schwann cells are essential for the maintenance of integrity and function of peripheral nerves such as the CNs. We hypothesize that brain-derived neurotrophic factor (BDNF) activa...

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Detalles Bibliográficos
Autores principales: Lin, Guiting, Zhang, Haiyang, Sun, Fionna, Lu, Zhihua, Reed-Maldonado, Amanda, Lee, Yung-Chin, Wang, Guifang, Banie, Lia, Lue, Tom F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4837308/
https://www.ncbi.nlm.nih.gov/pubmed/27141442
http://dx.doi.org/10.21037/tau.2016.02.03