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Twist-mediated Epithelial-mesenchymal Transition Promotes Breast Tumor Cell Invasion via Inhibition of Hippo Pathway

Twist is a key transcription factor for Epithelial-mesenchymal transition (EMT), which is a cellular de-differentiation program that promotes invasion and metastasis, confers tumor cells with cancer stem cell (CSC)-like characteristics, and increases therapeutic resistance. However, the mechanisms t...

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Detalles Bibliográficos
Autores principales: Wang, Yifan, Liu, Jingyi, Ying, Xuhua, Lin, Pengnian Charles, Zhou, Binhua P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4837350/
https://www.ncbi.nlm.nih.gov/pubmed/27094683
http://dx.doi.org/10.1038/srep24606