Identification of a residue crucial for the angiostatic activity of human mini tryptophanyl-tRNA synthetase by focusing on its molecular evolution

Human tryptophanyl-tRNA synthetase (TrpRS) exists in two forms: a full-length TrpRS and a mini TrpRS. We previously found that human mini, but not full-length, TrpRS is an angiostatic factor. Moreover, it was shown that the interaction between mini TrpRS and the extracellular domain of vascular endo...

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Detalles Bibliográficos
Autores principales: Nakamoto, Terumasa, Miyanokoshi, Miki, Tanaka, Tomoaki, Wakasugi, Keisuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4837363/
https://www.ncbi.nlm.nih.gov/pubmed/27094087
http://dx.doi.org/10.1038/srep24750

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4837363/
https://www.ncbi.nlm.nih.gov/pubmed/27094087
http://dx.doi.org/10.1038/srep24750

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