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A putative nitroreductase from the DosR regulon of Mycobacterium tuberculosis induces pro-inflammatory cytokine expression via TLR2 signaling pathway

Tuberculosis caused by Mycobacterium tuberculosis is a global encumbrance and it is estimated that nearly one third population of the world acts as a reservoir for this pathogen without any symptoms. In this study, we attempted to characterise one of the genes of DosR regulon, Rv3131, a FMN binding...

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Detalles Bibliográficos
Autores principales: Peddireddy, Vidyullatha, Doddam, Sankara Narayana, Qureshi, Insaf A., Yerra, Priyadarshini, Ahmed, Niyaz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4837367/
https://www.ncbi.nlm.nih.gov/pubmed/27094446
http://dx.doi.org/10.1038/srep24535