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Miniaturized iPS-Cell-Derived Cardiac Muscles for Physiologically Relevant Drug Response Analyses

Tissue engineering approaches have the potential to increase the physiologic relevance of human iPS-derived cells, such as cardiomyocytes (iPS-CM). However, forming Engineered Heart Muscle (EHM) typically requires >1 million cells per tissue. Existing miniaturization strategies involve complex ap...

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Detalles Bibliográficos
Autores principales: Huebsch, Nathaniel, Loskill, Peter, Deveshwar, Nikhil, Spencer, C. Ian, Judge, Luke M., Mandegar, Mohammad A., B. Fox, Cade, Mohamed, Tamer M.A., Ma, Zhen, Mathur, Anurag, Sheehan, Alice M., Truong, Annie, Saxton, Mike, Yoo, Jennie, Srivastava, Deepak, Desai, Tejal A., So, Po-Lin, Healy, Kevin E., Conklin, Bruce R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4837370/
https://www.ncbi.nlm.nih.gov/pubmed/27095412
http://dx.doi.org/10.1038/srep24726