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Miniaturized iPS-Cell-Derived Cardiac Muscles for Physiologically Relevant Drug Response Analyses
Tissue engineering approaches have the potential to increase the physiologic relevance of human iPS-derived cells, such as cardiomyocytes (iPS-CM). However, forming Engineered Heart Muscle (EHM) typically requires >1 million cells per tissue. Existing miniaturization strategies involve complex ap...
Autores principales: | Huebsch, Nathaniel, Loskill, Peter, Deveshwar, Nikhil, Spencer, C. Ian, Judge, Luke M., Mandegar, Mohammad A., B. Fox, Cade, Mohamed, Tamer M.A., Ma, Zhen, Mathur, Anurag, Sheehan, Alice M., Truong, Annie, Saxton, Mike, Yoo, Jennie, Srivastava, Deepak, Desai, Tejal A., So, Po-Lin, Healy, Kevin E., Conklin, Bruce R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4837370/ https://www.ncbi.nlm.nih.gov/pubmed/27095412 http://dx.doi.org/10.1038/srep24726 |
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