miRs-134 and -370 function as tumor suppressors in colorectal cancer by independently suppressing EGFR and PI3K signalling

Growth factor receptor signalling plays a central and critical role in colorectal cancer. Most importantly, the EGFR signalling cascade involving PI3K/AKT/mTOR and Raf/MEK/ERK pathways are particularly relevant, since they are commonly activated in several cancer entities, including colorectal cance...

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Detalles Bibliográficos
Autores principales: El-Daly, Sherien M., Abba, Mohammed L., Patil, Nitin, Allgayer, Heike
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4837379/
https://www.ncbi.nlm.nih.gov/pubmed/27095166
http://dx.doi.org/10.1038/srep24720

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4837379/
https://www.ncbi.nlm.nih.gov/pubmed/27095166
http://dx.doi.org/10.1038/srep24720

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