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A uniform survey of allele-specific binding and expression over 1000-Genomes-Project individuals

Large-scale sequencing in the 1000 Genomes Project has revealed multitudes of single nucleotide variants (SNVs). Here, we provide insights into the functional effect of these variants using allele-specific behaviour. This can be assessed for an individual by mapping ChIP-seq and RNA-seq reads to a p...

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Detalles Bibliográficos
Autores principales: Chen, Jieming, Rozowsky, Joel, Galeev, Timur R., Harmanci, Arif, Kitchen, Robert, Bedford, Jason, Abyzov, Alexej, Kong, Yong, Regan, Lynne, Gerstein, Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4837449/
https://www.ncbi.nlm.nih.gov/pubmed/27089393
http://dx.doi.org/10.1038/ncomms11101