Cargando…
Crystal structure of glycogen debranching enzyme and insights into its catalysis and disease-causing mutations
Glycogen is a branched glucose polymer and serves as an important energy store. Its debranching is a critical step in its mobilization. In animals and fungi, the 170 kDa glycogen debranching enzyme (GDE) catalyses this reaction. GDE deficiencies in humans are associated with severe diseases collecti...
| Autores principales: | , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2016
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4837477/ https://www.ncbi.nlm.nih.gov/pubmed/27088557 http://dx.doi.org/10.1038/ncomms11229 |