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Stress ulcer prophylaxis with a proton pump inhibitor versus placebo in critically ill patients (SUP-ICU trial): study protocol for a randomised controlled trial

BACKGROUND: Critically ill patients in the intensive care unit (ICU) are at risk of clinically important gastrointestinal bleeding, and acid suppressants are frequently used prophylactically. However, stress ulcer prophylaxis may increase the risk of serious adverse events and, additionally, the qua...

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Detalles Bibliográficos
Autores principales: Krag, Mette, Perner, Anders, Wetterslev, Jørn, Wise, Matt P., Borthwick, Mark, Bendel, Stepani, Pelosi, Paolo, Keus, Frederik, Guttormsen, Anne Berit, Schefold, Joerg C., Møller, Morten Hylander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4837508/
https://www.ncbi.nlm.nih.gov/pubmed/27093939
http://dx.doi.org/10.1186/s13063-016-1331-3