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CRTC1 gene is differentially methylated in the human hippocampus in Alzheimer’s disease
BACKGROUND: CRTC1 (CREB regulated transcription coactivator 1) gene plays a role in synaptic plasticity, learning and long-term memory formation in the hippocampus. Recently, CRTC1 has been shown to be downregulated in Alzheimer’s disease (AD). Nevertheless, the mechanisms underlying CRTC1 dysregula...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4837517/ https://www.ncbi.nlm.nih.gov/pubmed/27094739 http://dx.doi.org/10.1186/s13195-016-0183-0 |