CRTC1 gene is differentially methylated in the human hippocampus in Alzheimer’s disease

BACKGROUND: CRTC1 (CREB regulated transcription coactivator 1) gene plays a role in synaptic plasticity, learning and long-term memory formation in the hippocampus. Recently, CRTC1 has been shown to be downregulated in Alzheimer’s disease (AD). Nevertheless, the mechanisms underlying CRTC1 dysregula...

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Detalles Bibliográficos
Autores principales: Mendioroz, Maite, Celarain, Naiara, Altuna, Miren, Sánchez-Ruiz de Gordoa, Javier, Zelaya, María Victoria, Roldán, Miren, Rubio, Idoya, Larumbe, Rosa, Erro, María Elena, Méndez, Iván, Echávarri, Carmen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4837517/
https://www.ncbi.nlm.nih.gov/pubmed/27094739
http://dx.doi.org/10.1186/s13195-016-0183-0

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