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Calreticulin Translocation Aggravates Endoplasmic Reticulum Stress-associated Apoptosis during Cardiomyocyte Hypoxia/Reoxygenation

BACKGROUND: Calreticulin (CRT) is major Ca(2+)-binding chaperone mainly resident in the endoplasmic reticulum (ER) lumen. Recently, it has been shown that non-ER CRT regulates a wide array of cellular responses. We previously found that CRT was up-regulated during hypoxia/reoxygenation (H/R) and thi...

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Detalles Bibliográficos
Autores principales: Xu, Fei-Fei, Liu, Xiu-Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4837866/
https://www.ncbi.nlm.nih.gov/pubmed/25635431
http://dx.doi.org/10.4103/0366-6999.150103